What is Molecular Dynamics Simulation?
April 26, 2019
Written By Nicholas Chavez
A physicist, computer scientist, and biomedical engineer walk into a bar…and begin to play pool. The biomedical engineer takes aim and sends the cue ball into the rack, scattering the other fifteen balls across the table. The physicist watches as the c...
What is a PDB file?
March 29, 2019
Written By Vince Parish
Our Instagram and blog often make reference to PDB files. We briefly mentioned the Protein Data Bank (also abbreviated as PDB) in our previous blog about docking which may have generated some confusion. This blog post will explain the use of PDB files ...
March 14, 2019
Written By Christian Gil and Jacob Byerly
Machine Learning and Cloud Computing are a couple of the hottest topics in computational science right now, but one of the most important topics in computational drug design is something you may not have even heard of! Protein-protein docking — often s...
Caffeine: The Good, The Bad, and The History
Jan. 24, 2019
Written By Vince Parish, Jacob Byerly, and Eduardo Priego
Caffeine has been consumed by humans all over the world for thousands of years. An ancient Chinese legend says the Emperor Shen Nung first discovered tea in 2437 BCE when the wind blew leaves into his boiling water. He was intrigued by the pleasant aro...
AI: Neural Networks
Jan. 10, 2019
Written By Juan Zambrano, Eduardo Priego, Jacob, Byerly, and Vince Parish
Since the 1927 release of the classic silent film Metropolis, the concept of Artificial Intelligence (AI) has been heavily explored in various forms of media. Until recently, however, limited computational power has kept it squarely in the realm of sci...
The Adaptive Immune System
Dec. 20, 2018
Written By Jordan Graves, Jacob Byerly, Vince Parish, and Eduardo Priego
Throughout the day our bodies are bombarded with any number of foreign pathogens, some of which are harmless, others of which are potentially lethal. We are constantly fighting off these invaders to keep ourselves healthy — a good thing to keep in mind...
"Starting Up" with Cloud Computing
Dec. 7, 2018
Written By Naren Makkapati, Vince Parish, and Jacob Byerly
"Cloud computing has long since left the “buzzword stage” of its life cycle, with most major companies integrating it into their technology and workflow to some degree. Cloud computing is often described through a number of analogies — from a “data lak...
Founders and Contributors of Bacteriology
Nov. 15, 2018
Written By Susana Kaufmann, Jacob Byerly, and Vincent Parish
As Thanksgiving approaches, we at Macromoltek would like to express our appreciation for some of the founding scientists of modern medicine. Without their commitment to the discipline, it would not be where it is today. There are many iconic figures in...
What is Protein Purification?
Oct. 25, 2018
Written By Vince Parish and Jacob Byerly
There is an adage in biochemistry: “Never waste pure thoughts on an impure protein” (1). The straightforward definition of protein purification is the isolation of only one type of molecule from the soup of many molecules — but the process itself is ra...
The Difference Between Vaccines and Antibody Therapeutics
Oct. 8, 2018
Written By Jacob Byerly and Vince Parish
Vaccines are considered to be among the greatest medical advances in the past several centuries. They have effectively eliminated some of the most deadly diseases ever to scourge humanity. Study of the immune system has led to the development of antibo...